4-HO-MiPT
Common Names: Hydroxy-N-methyl-N-isopropyltryptamine, HO-MiPT, Miprocin, It, AcO-DMT
Psychoactive Effects
Positive Effects
- Euphoria
Neutral Effects
- Visual hallucinations
- Time distortion
- Synesthesia
- Altered thought patterns
- Enhanced sensory perception
Negative Effects
- Anxiety
Dosage Guidelines
| Route | Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|---|
| Oral | 5-10 mg | 10-20 mg | 20-35 mg | 35-50 mg | 50+ mg |
Duration
| Phase | Duration |
|---|---|
| Onset | 30-60 minutes |
| Peak | 2-4 hours |
| Total | 4-8 hours |
| After effects | 2-4 hours |
Pharmacology
Mechanism of Action: 4-HO-MiPT acts as a partial agonist at serotonin 5-HT2A receptors, similar to psilocin.
Metabolism: Metabolized in the liver primarily by CYP2D6 and CYP3A4 enzymes.
Half-life: Approximately 2-3 hours, with effects typically lasting 4-8 hours.
Bioavailability: ~70% when taken orally, with peak plasma concentrations reached within 1-2 hours.
Risks and Harm Reduction
⚠️ Important: Always practice harm reduction. Start with low doses, test your substances, and ensure a safe set and setting. Never use alone.
Legal Status
Disclaimer: Legal status varies by jurisdiction and may change. This information is for educational purposes only.
References
- • Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264-355.
- • Carbonaro, T. M., & Gatch, M. B. (2016). Neuropharmacology of N,N-dimethyltryptamine. Brain Research Bulletin, 126, 74-88.
- • Information compiled from PsychonautWiki