4-FA
Common Names: Fluoroamphetamine, FA, FMP, Fluoroamphetamine, PAL-303
Psychoactive Effects
Positive Effects
- Euphoria
Neutral Effects
- Increased energy
- Enhanced focus
- Reduced appetite
- Increased heart rate
- Pupil dilation
- Dry mouth
Negative Effects
- Anxiety
- Depression
Dosage Guidelines
| Route | Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|---|
| Oral | 20-40 mg | 40-80 mg | 80-150 mg | 150-250 mg | 250+ mg |
Duration
| Phase | Duration |
|---|---|
| Onset | 30-60 minutes |
| Peak | 2-4 hours |
| Total | 4-8 hours |
| After effects | 6-12 hours |
Pharmacology
Mechanism of Action: 4-FA acts as a releasing agent and reuptake inhibitor of serotonin, norepinephrine, and dopamine, with greater serotonin activity than traditional amphetamines.
Metabolism: Metabolized in the liver primarily by CYP2D6 and CYP3A4 enzymes.
Half-life: Approximately 6-8 hours, with effects typically lasting 4-8 hours.
Bioavailability: ~80% when taken orally, with peak plasma concentrations reached within 1-2 hours.
Risks and Harm Reduction
⚠️ Important: Always practice harm reduction. Start with low doses, test your substances, and ensure a safe set and setting. Never use alone.
Legal Status
Disclaimer: Legal status varies by jurisdiction and may change. This information is for educational purposes only.
References
- • de la Torre, R., et al. (2004). Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition. Therapeutic Drug Monitoring, 26(2), 137-144.
- • Green, A. R., et al. (2003). The pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy'). Pharmacological Reviews, 55(3), 463-508.
- • Information compiled from PsychonautWiki