2C-E
Common Names: Dimethoxy-4-ethylphenethylamine, C-E, Aquarust, Eternity, It
Psychoactive Effects
Positive Effects
- Euphoria
- Pleasure
Neutral Effects
- Visual hallucinations
- Time distortion
- Enhanced colors
- Geometric patterns
- Altered body perception
- Enhanced tactile sensations
Negative Effects
- Anxiety
Dosage Guidelines
| Route | Threshold | Light | Common | Strong | Heavy |
|---|---|---|---|---|---|
| Oral | 5-10 mg | 10-20 mg | 20-35 mg | 35-50 mg | 50+ mg |
Duration
| Phase | Duration |
|---|---|
| Onset | 30-90 minutes |
| Peak | 3-5 hours |
| Total | 6-10 hours |
| After effects | 3-6 hours |
Pharmacology
Mechanism of Action: 2C-E acts as a partial agonist at serotonin 5-HT2A and 5-HT2C receptors, with some activity at 5-HT2B receptors.
Metabolism: Metabolized in the liver primarily by CYP2D6 and CYP2C19 enzymes.
Half-life: Approximately 3-5 hours, with effects typically lasting 6-10 hours.
Bioavailability: ~70% when taken orally, with peak plasma concentrations reached within 1-2 hours.
Risks and Harm Reduction
⚠️ Important: Always practice harm reduction. Start with low doses, test your substances, and ensure a safe set and setting. Never use alone.
Legal Status
Disclaimer: Legal status varies by jurisdiction and may change. This information is for educational purposes only.
References
- • Shulgin, A. T., & Shulgin, A. (1991). PiHKAL: A Chemical Love Story. Transform Press.
- • Nichols, D. E. (2016). Psychedelics. Pharmacological Reviews, 68(2), 264-355.
- • Information compiled from PsychonautWiki